The COVID-19 pandemic has strongly affected all walks of life and has devastated lives globally. The pandemic has further increased economic and social inequality in a vulnerable society. As per The World Economic Forum’s Global Gender Report 2021, it is estimated that the global economy has been set back by up to 39 years during the pandemic era. Furthermore, healthcare access has been disrupted for women and girls, a subject which has been ignored for a long time. Precipitating factors further led to a rise in gender-based violence and sex-based marginalization. Health inequalities related to economic status and social and cultural environments are increasing. These differences are attributable to social disparities between men and women, which often assume different functions and tasks and are therefore exposed to different morbidity factors. Others are innate to biological, genetic, hormonal, and metabolic dissimilarities or acquired (environmental) dissimilarities. It appears that both social and biological differences play a role; however, the border between the two is difficult to delimit. Thus, long-term measures are needed to balance between professional and personal life for the economic independence of women.